Leishmania_species. Leishmania_species

Leishmania is an intracellular protistan parasite affecting macrophages and dendritic cells. Leishmania infections result in a wide range of symptoms in human hosts depending on the species or strain involved. Several whole genome sequences currently exist for Leishmania species. To correct sequencing and assembly errors and examine interstrain variation pair-end sequencing runs were performed with 76 base pair reads on the Illumina genome analyzer.. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/. The sample with accession ERS001888 has been described in the following article, Franssen SU, Durrant C, Stark O, Moser B, Downing T, Imamura H, et al. (2020). Global genome diversity of the Leishmania donovani complex. eLife 9: e51243. (https://elifesciences.org/articles/51243) and its further analysis can be freely submitted for publication. For information on the proper use of data shared by the Wellcome Trust Sanger Institute (including information on acknowledgement), please see http://www.sanger.ac.uk/datasharing/ Please cite the publication when using the data.

利什曼原虫（Leishmania）是一类侵染巨噬细胞与树突状细胞的细胞内原生寄生虫。利什曼原虫感染可根据所涉及的虫种或虫株，在人类宿主中引发多种不同的临床症状。目前已有多种利什曼原虫的全基因组序列被解析。为校正测序与组装误差，并探究株间遗传变异，研究人员在Illumina基因组分析仪上开展了76碱基对读长的双端测序（Pair-end sequencing）实验。本数据集属于预出版阶段发布的数据。如需了解惠康信托桑格研究所（Wellcome Trust Sanger Institute）共享预发布数据的规范使用要求（含出版暂缓相关细则），请访问http://www.sanger.ac.uk/datasharing/。登录号为ERS001888的样本已在如下文献中被报道：Franssen SU、Durrant C、Stark O、Moser B、Downing T、Imamura H等（2020）. 《杜氏利什曼原虫复合群的全球基因组多样性》. eLife 9: e51243（https://elifesciences.org/articles/51243），针对该样本的后续分析可自由投稿发表。如需了解惠康信托桑格研究所共享数据的规范使用要求（含致谢相关说明），请再次访问http://www.sanger.ac.uk/datasharing/。使用本数据集时，请引用上述发表文献。