One-Pot Cascade Approach to Phen­anthridine-Fused Qui­nazo­linimi­niums from Heteroenyne-Allenes

A one-pot
cascade method to obtain functionalized phen­anthri­dine-fused
quinazoliniminiums from a variety of heteroenyne-allenes is described.
This protocol involves formation of C–N and C–C bonds
in a single step in the presence of a Lewis acid and trace water to
afford pentacyclic title compounds in moderate to good yields.

本研究报道了一种可由多种杂烯炔-联烯类底物制备官能化菲啶稠合喹唑啉亚胺鎓盐的一锅级联反应方法。该合成策略可在路易斯酸与痕量水的存在下，通过一步反应同时构建碳氮键与碳碳键，最终以中等至优异的收率得到五环骨架的目标产物。