Supplementary Material for: Characteristics and visual prognosis of pediatric open globe injury in Shanghai, China

Introduction To describe the characteristics of open globe injury and the relationship between the complications and visual outcomes in children with this type of injury. Methods This was a retrospective chart review of 1664 children, under the age of 16 years, who were hospitalized for open globe injury between January 1, 2007, and December 31, 2015. Each patient’s age, sex, cause and agent of injury, complications, visual acuity, and classification of ocular trauma were collected for review and analysis. Results The mean age was 5.6 ± 3.4 years. Right eyes were particularly vulnerable to injury (right eye:left eye ratio = 1.2:1). Traumatic cataract was the most common complication. The average initial and final best-corrected visual acuity (BCVA) were logMAR 2.04 ± 0.78 and logMAR 1.74 ± 0.88, respectively. Logistic regression analysis showed that hyphema (OR = 1.850), iris prolapse (OR = 1.702), vitreous hemorrhage (OR = 9.703), retinal detachment (OR = 11.938), endophthalmia (OR = 5.377), intraocular foreign body (OR = 3.346), and initial visual acuity < 0.05 (OR = 9.017) were risk factors for visual acuity < 0.05 at hospital discharge. Conclusion Open globe injury was most frequent in preschool children and boys. Right eyes were more vulnerable than left eyes. Poor visual outcomes were associated with hyphema, iris prolapse, vitreous hemorrhage, retinal detachment, endophthalmia, intraocular foreign body, and an initial visual acuity < 0.05.

本研究旨在探讨儿童开放性眼球损伤（open globe injury）的临床特征，以及此类损伤患儿的并发症与视觉预后之间的关联。
方法：本研究为回顾性病历分析研究，纳入2007年1月1日至2015年12月31日期间因开放性眼球损伤住院的1664名16岁以下儿童。收集所有受试者的年龄、性别、损伤原因与致伤因子、并发症、视力及眼外伤分型等资料并进行分析。
结果：研究对象的平均年龄为5.6±3.4岁，右眼更易受损伤（右眼与左眼损伤比例为1.2:1）。外伤性白内障为最常见的并发症。受试者初始与最终的平均最佳矫正视力（best-corrected visual acuity, BCVA）分别为logMAR 2.04±0.78与logMAR 1.74±0.88。逻辑回归分析显示，前房积血（hyphema，OR=1.850）、虹膜脱出（iris prolapse，OR=1.702）、玻璃体积血（vitreous hemorrhage，OR=9.703）、视网膜脱离（retinal detachment，OR=11.938）、眼内炎（endophthalmia，OR=5.377）、眼内异物（intraocular foreign body，OR=3.346）以及初始视力<0.05（OR=9.017）均为出院时视力<0.05的独立危险因素。
结论：开放性眼球损伤在学龄前儿童及男性儿童中发病率最高，右眼较左眼更易受损。不良视觉预后与前房积血、虹膜脱出、玻璃体积血、视网膜脱离、眼内炎、眼内异物及初始视力<0.05显著相关。