SH1441933.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE 为界定、识别、交流及处理基于DNA的物种假说（Species Hypotheses，后文简称SH）提供了一套统一的标准化方法。国际核酸序列数据库中的全部真菌ITS序列，均通过应用一系列动态距离阈值（0.5%~3.0%）被聚类至近似物种水平的分类单元。所有SH均会被赋予唯一且稳定的DOI格式名称，其分类学与生态学注释信息将通过分布式网络第三方注释工作完成验证。系统将结合SH内所有序列的鉴定结果，尽可能为其匹配对应的分类单元名称及其分类层级（如门、纲、目等）并建立关联。系统将自动或手动选取一条序列作为每个SH的代表序列。上述代表序列已对外发布（访问链接：https://unite.ut.ee/repository.php），可供科研群体用于本地序列相似性搜索、下一代测序分析流程等科研场景。随着公共真菌ITS序列数据量的增长，该系统及其数据集将自动完成更新。