遇见数据集

Genomic Resources for Global and Local Ancestry Estimation in a Captive Baboon Colony

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Zenodo2024-05-14 更新2026-05-26 收录
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VCF files mapped to Panubis1.0 with 881 olive (Papio anubis) and yellow (Papio cynocephalus) baboons from the Southwest National Primate Research Center. VCF files were generated in two separate pipelines, first using Beagle 4.1 and Beagle 5.4 and additionally SHAPEIT5/IMPUTE5 to test if a pedigree-aware software reduced the number of evident phase switch errors. VCFs here have been phased and imputed in their respective pipelines, filtered for imputation accuracy with markers with less than 0.7 confidence removed using BCFTools, and then phase switch corrected using Tractor. Genomic resources (AIMs and Fixed markers) are based off of Panubis1.0 coordinates. Local ancestry estimation completed by RFMix and then phase-switch-corrected using Tractor.

本数据集包含比对至Panubis1.0参考基因组的变异识别格式(Variant Call Format,VCF)文件,样本来自西南国家灵长类研究中心的881只橄榄狒狒(*Papio anubis*)与黄狒狒(*Papio cynocephalus*)。 该数据集的VCF文件通过两套独立分析流程生成:首先分别使用Beagle 4.1、Beagle 5.4,以及SHAPEIT5/IMPUTE5进行处理,以验证系谱感知软件是否可减少显著的相位切换错误。 本数据集收录的VCF文件已在各自流程中完成相位分型与基因型填充,随后通过BCFTools过滤掉置信度低于0.7的标记以保障填充准确性,再使用Tractor完成相位切换校正。 基因组相关资源(祖先信息标记与固定标记)均基于Panubis1.0的基因组坐标构建;本地祖先估计通过RFMix完成,随后再次使用Tractor进行相位切换校正。

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Zenodo
创建时间:
2024-01-11
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