Figure S1 - Efficacy of a Marine Bacterial Nuclease against Biofilm Forming Microorganisms Isolated from Chronic Rhinosinusitis

Three-dimensional rotation showing micro-organisms associated with the outer layer of a mucosal biopsy. Bacterial DNA was hybridized with the EUB338 PNA-FISH probe, and appears green in the image. Host cell nuclei were counterstained blue. Bacterial cells (punctate green staining) are seen interacting with cells on the surface of the biopsy. (AVI)

本三维旋转演示展示了黏附于黏膜活检样本外层的微生物。细菌DNA与EUB338肽核酸荧光原位杂交（PNA-FISH）探针杂交后，在图像中呈现绿色。宿主细胞核经复染后呈蓝色。可见细菌细胞（呈点状绿色染色）与活检样本表面的细胞发生相互作用。(AVI)