mRNA expression in rat proximal femoral growthplate after mid-shaft fracture

Mid-shaft fracture stimulates bone lengthening by increasing linear growth at the growthplate. This project studied changes in mRNA in the proximal growthplate after a mid-shaft fracture in a rat model. Keywords: time course, fracture, growthplate, rat Study of rat proximal femoral growthplate after mid-shaft fracture in 4 week old Sprague-Dawley female rats. RNA from two rats were pooled for each sample. Proximal femoral growthplate was studied from the fractured femora and the intact contralateral femora.

骨干中段骨折可通过提升生长板（growthplate）的线性生长速率以促进骨延长。本研究以大鼠为模型，对骨干中段骨折后近端生长板内的mRNA表达变化展开探究。关键词：时间进程、骨折、生长板、大鼠。本研究以4周龄雌性斯普拉格-道利（Sprague-Dawley）大鼠为实验对象，开展其骨干中段骨折后股骨近端生长板的相关研究。每个样本均混合两只大鼠的RNA进行制备。本研究分别采集骨折侧股骨与对侧健侧股骨的股骨近端生长板样本进行分析。