Percent changes (Δ-values are differences between means) in protein levels and proteolytic activity of Separase after IM treatment when compared to corresponding untreated cells.
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1 Δ-values were calculated from significant data sets diagrammed in Fig 1. All values are normalized to Actin.2 for representative corresponding immunostained Western blots see Fig 1.3 calculated quotient of Separase proteolytic activity [%] / Separase protein level [%]. Example (K526): (100+9.1)/(100–56.9) = 2.5Abbreviations: d, days; h, hours; IM, imatinib; +, increase;-, decrease.The confidence interval (95%CI) is given in parentheses.** Since the CI of the denominator includes zero, it is not possible to compute the CI of this quotient.Percent changes (Δ-values are differences between means) in protein levels and proteolytic activity of Separase after IM treatment when compared to corresponding untreated cells.
1. Δ值(Δ-values)由图1所示的显著性数据集计算得到,所有数值均以肌动蛋白2(Actin)为参照进行归一化处理。
2. 代表性经免疫染色的免疫印迹(immunostained Western blots)的相关结果见图1。
3. 该值为分离酶(Separase)蛋白水解活性百分比与分离酶蛋白水平百分比的计算比值。示例(K526细胞):(100+9.1)/(100–56.9) = 2.5。
缩写说明:d代表天(days),h代表小时(hours),IM代表伊马替尼(imatinib);“+”表示升高,“-”表示降低。
括号内标注了95%置信区间(95% confidence interval, 95%CI)。** 由于分母的置信区间包含0,因此无法计算该比值的置信区间。**
伊马替尼处理后,分离酶的蛋白水平与蛋白水解活性的百分比变化(Δ值为各组均值间的差值)均以对应的未处理细胞为对照进行计算。
创建时间:
2015-12-03



