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2024年PD猕猴模型手术后第0天脑部核磁数据

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国家非人灵长类实验动物资源库2025-09-02 更新2026-02-07 收录
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https://nhp.kiz.ac.cn/57/db
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资源简介:
本数据集为收集到的2024年中国科学院昆明动物研究所胡新天团队对5只猕猴(青年2只、中年3只)用于PD模型造模手术后第0天的脑部核磁共振扫描数据,主要扫描序列包括T1、T2、DWI等。 数据质量:数据集中的所有数据的实验猕猴均来自中国科学院昆明动物研究所实验动物中心,该中心于2008年通过国际AAALAC认证,2018年全国首家通过CNAS认可,实验动物管理达到国际管理规范。 数据采集使用联影uMR790磁共振成像仪器,该设备质量符合国家相关标准,所有设备操作者均接受上岗培训,以确保获得合格的高清晰度图像。 数据来源:a.物种:猕猴 b.实验动物信息 样本数量:5只 年龄分布:4-12岁2只,13-19岁3只 重量分布:7-13Kg 性别分布:雄性4只,雌性1只 c.扫描仪规格 扫描仪类型:联影uMR790 线圈:12通道膝关节线圈,12通道猕猴专用头线圈 d.扫描程序 动物福利伦理:由中国科学院昆明动物研究所实验动物福利伦理委员会批准。 动物护理和饲养:中国科学院昆明动物研究所实验动物中心 麻醉方式:舒泰5-8mg/kg 麻醉和扫描间隔时间:3-5分钟 扫描体位:俯卧头先进 数据生产方式:原始数据,未经加工处理。 时间范围:2024年05月30日至2024年07月22日

This dataset contains brain MRI scan data collected in 2024 by the team led by Hu Xintian from the Kunming Institute of Zoology, Chinese Academy of Sciences. The data were acquired from 5 rhesus macaques (2 young, 3 middle-aged) on post-operative day 0 after Parkinson's disease (PD) modeling surgery. The main scanning sequences include T1-weighted imaging, T2-weighted imaging, diffusion-weighted imaging (DWI), etc. Data Quality: All experimental macaques in this dataset are sourced from the Laboratory Animal Center of Kunming Institute of Zoology, Chinese Academy of Sciences. This center received Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) accreditation in 2008 and became the first institution in China to obtain China National Accreditation Service for Conformity Assessment (CNAS) accreditation in 2018, with its laboratory animal management meeting international standardized requirements. Data Acquisition: The scans were performed using the United Imaging uMR790 magnetic resonance imaging system, which complies with relevant national standards. All equipment operators completed mandatory on-the-job training to ensure the acquisition of high-quality, high-definition images. Data Sources: a. Species: Rhesus macaque b. Experimental Animal Details - Sample size: 5 individuals - Age distribution: 2 individuals aged 4–12 years, 3 individuals aged 13–19 years - Weight distribution: 7–13 kg - Sex distribution: 4 males, 1 female c. Scanner Specifications - Scanner model: United Imaging uMR790 - Coils used: 12-channel knee coil, 12-channel dedicated rhesus macaque head coil d. Scanning Protocols - Animal Welfare Ethics Approval: Approved by the Laboratory Animal Welfare Ethics Committee of Kunming Institute of Zoology, Chinese Academy of Sciences - Animal Care and Husbandry: Provided by the Laboratory Animal Center of Kunming Institute of Zoology, Chinese Academy of Sciences - Anesthesia protocol: Administered with Zoletil at a dose of 5–8 mg/kg - Interval between anesthesia administration and scanning: 3–5 minutes - Scanning position: Prone, head-first - Data type: Raw, unprocessed data - Data collection period: May 30, 2024 to July 22, 2024
提供机构:
中国科学院昆明动物研究所
创建时间:
2025-09-02
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