Neuroendocrine carcinoma, NOS - Female, 69 - Tissue image [530073002587121]

This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 69Clinical description: Tumors of liver. Suspicion of metastases.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Neuroendocrine carcinoma, NOSResult of the histopathological examination: Metastasis of neuroendocrine carcinoma (probably from lung) to liver: CKAE1/AE3+ (dot-like), SYN+, CHR weak +, TTF1+, Ki-67 90%.Sample:Material: FFPECollecting method: Core-needle biopsyTopography: DIGESTIVE ORGANSOrgan: LIVER AND INTRAHEPATIC BILE DUCTSTissue: LiverType of staining: positive/IHCStaining: Not applicableAntibody: CK PAN (AE1/AE3)Technology:Equipment: Pannoramic 1000Lens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存档于ZMDL-GUMED的肝脏及肝内胆管组织样本的组织病理学图像。该样本图像采用Pannoramic 1000玻片扫描仪以20倍放大倍率拍摄，并以DICOM格式存储。

患者与相关诊断详情如下：
患者基本信息：年龄69岁，女性；临床描述为肝脏肿瘤，疑似发生转移。
病理分类：依据ICD-O-3.2分类标准，分类编码为腺瘤与腺癌类病变；最终诊断为未特指型神经内分泌癌（Neuroendocrine carcinoma, NOS）。
组织病理学检查结果：肝脏可见神经内分泌癌转移灶（原发灶大概率来源于肺部）；免疫组化标记结果为CKAE1/AE3+（点状染色）、SYN+、CHR弱阳性、TTF1+，Ki-67增殖指数为90%。

样本相关信息：
样本材质为福尔马林固定石蜡包埋（Formalin-Fixed Paraffin-Embedded, FFPE）组织，采集方式为芯针穿刺活检。
样本所属解剖部位为消化器官，具体器官为肝脏及肝内胆管，受试组织为肝脏组织。
染色方案为免疫组化（Immunohistochemistry, IHC）阳性染色，本次未明确指定具体染色流程，所用抗体为CK PAN（AE1/AE3）。
成像技术参数：使用设备为Pannoramic 1000，镜头放大倍数为20倍。
样本来源机构：格但斯克医科大学。