MT1-MMP induces malignant transformation in Mammary cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5095
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资源简介:
Expression of the MT1-MMP gene induces a significant upregulation of of oncogenes and tumorignenic genes in 184B5-MT1 cells. Keywords: Genetic modification Three biological replicates of untransfected Mammary cell line compared to MT1-MMP transfected Mammary cell line. Singel channel data from the illumina platform. After normalisation and t-tests differential gene expression was determined between the two groups using p-values and fold change.
MT1-MMP基因的表达可在184B5-MT1细胞中诱导癌基因与致瘤基因的显著上调。
关键词:基因修饰(Genetic modification)
本数据集以三组未转染乳腺细胞系的生物学重复样本为对照,与转染MT1-MMP的乳腺细胞系的三组生物学重复样本进行对比,数据来源于Illumina(illumina)平台的单通道测序数据。经过标准化处理与t检验后,本研究通过p值与倍数变化(fold change)确定了两组间的差异基因表达情况。
创建时间:
2012-03-16



