Plasma and faecal metabolomic data, and intestinal microbial communities of mice exposed to cold temperature or RT.

Mice were allocated into three groups: the room temperature (RT) group maintained at 24°C; the cold group exposed to 4°C for four hours daily, with the remaining time spent at RT; and the continuous cold (CC) group kept in a sustained cold (4°C) environment. After four-week intervention, mice were anaesthetized, and plasma and faecal samples were harvested for untargeted metabolomics. Faecal samples were also collected for shotgun metagenomics.

将小鼠分为三组：室温（RT）组，饲养环境维持于24℃；寒冷暴露组，每日暴露于4℃环境4小时，其余时间置于室温环境；持续寒冷（CC）组，始终处于4℃的持续寒冷环境中。经过4周干预后，对小鼠实施麻醉，采集血浆及粪便样本用于非靶向代谢组学（untargeted metabolomics）分析；同时收集粪便样本用于鸟枪法宏基因组学（shotgun metagenomics）分析。