Isoelectric point of pOPAR is from Table 1. Isoelectric points of OPAR, P0 and P3 were derived as described in Experimental Procedures. IC50 values were derived from the data shown in Figures 7 and 8.
The CLP302-253 IC50 for the enzymatic activity of recombinant α, β, γ and δ PI3K isoforms was determined in ADP-Glo Kinase assay. The assay was performed at least 3 times. The CPL302-253 binding affin