Additional file 11 of Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types

Table S6. Disease-associated cell types identified by the GSC method with an FDR of 10 %. DISEASE: Disease name. CELL_TYPE: Cell-type name. P_VALUE: Unadjusted P value computed using the GSC method. Q_VALUE: Minimum FDR at which the association can be declared significant, computed using the Benjaminiâ Hochberg procedure for multiple testing. SIG_GSO: Whether the association is declared significant using the GSO method at an FDR of 10 %. SIG_TEXT: Whether the association is declared significant using text-mining at an FDR of 10 %. (XLS 78 kb)

补充表S6：采用错误发现率（False Discovery Rate, FDR）为10%的GSC方法鉴定得到的疾病相关细胞类型。各列说明如下：DISEASE：疾病名称；CELL_TYPE：细胞类型名称；P_VALUE：通过GSC方法计算得到的未校正P值；Q_VALUE：经本雅明尼-霍奇伯格（Benjamini-Hochberg）多重检验校正程序计算得到的、可判定该细胞类型-疾病关联具有显著性的最小错误发现率；SIG_GSO：是否在FDR=10%的阈值下，通过GSO方法判定该关联具有显著性；SIG_TEXT：是否在FDR=10%的阈值下，通过文本挖掘方法判定该关联具有显著性。（文件格式为XLS，大小78 KB）