Additional file 11 of Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types
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Table S6. Disease-associated cell types identified by the GSC method with an FDR of 10 %. DISEASE: Disease name. CELL_TYPE: Cell-type name. P_VALUE: Unadjusted P value computed using the GSC method. Q_VALUE: Minimum FDR at which the association can be declared significant, computed using the Benjaminiâ Hochberg procedure for multiple testing. SIG_GSO: Whether the association is declared significant using the GSO method at an FDR of 10 %. SIG_TEXT: Whether the association is declared significant using text-mining at an FDR of 10 %. (XLS 78 kb)
补充表S6:采用错误发现率(False Discovery Rate, FDR)为10%的GSC方法鉴定得到的疾病相关细胞类型。各列说明如下:DISEASE:疾病名称;CELL_TYPE:细胞类型名称;P_VALUE:通过GSC方法计算得到的未校正P值;Q_VALUE:经本雅明尼-霍奇伯格(Benjamini-Hochberg)多重检验校正程序计算得到的、可判定该细胞类型-疾病关联具有显著性的最小错误发现率;SIG_GSO:是否在FDR=10%的阈值下,通过GSO方法判定该关联具有显著性;SIG_TEXT:是否在FDR=10%的阈值下,通过文本挖掘方法判定该关联具有显著性。(文件格式为XLS,大小78 KB)



