RNA sequencing of young and old lung ILC2 cells

ILC2 cells from young and old mouse lungs were analysed and revealed altered transcriptome of old ILC2 compared to the young. Overall design: ILC2 from lungs of young (8 weeks) and old (20 months) female C57BL/6 mice were harvested. ILC2 were sorted

本研究对年轻与老年小鼠肺部的2型固有淋巴细胞（ILC2）进行了分析，结果显示，与年轻小鼠的ILC2相比，老年小鼠ILC2的转录组（transcriptome）存在显著改变。实验整体设计：从8周龄年轻雌性C57BL/6小鼠与20月龄老年雌性C57BL/6小鼠的肺部中分离收集ILC2，随后对ILC2进行分选。