Canine nasal microbiota. undefined

Nasal samples were collected from dogs with and without dermatological conditions at baseline and follow-up. The samples underwent 16S rRNA gene sequencing. Microbiota analyses showed that the follow-up nasal samples of dogs with dermatological conditions had decreased microbiota diversity and abundance compared to dogs without dermatological conditions. This work shows that there was a dysbiosis in the nasal microbiota of dogs with dermatological conditions.本研究于基线及随访两个时间节点，分别从罹患皮肤病与未罹患皮肤病的犬只体内采集鼻腔样本。随后对所有样本开展16S核糖体RNA（16S rRNA）基因测序。微生物组分析结果显示，与未患皮肤病的犬只相比，罹患皮肤病的犬只在随访阶段采集的鼻腔样本中，其微生物组的多样性与丰度均出现下降。本研究证实，罹患皮肤病的犬只鼻腔微生物组存在菌群失调现象。