Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion

ChEBI2016-07-12 更新2026-07-12 收录

糖原代谢

疾病模型构建

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-4389 数据链接链接失效反馈

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资源简介：

Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion

创建时间：

2016-07-12

Effect of AT2220 co-administration on rhGAA-mediated glycogen reduction (% change from Baseline) in GAA KO mice.

庞贝病治疗

糖原代谢

Twelve-week old male GAA KO mice were administered vehicle (water) or AT2220 via oral gavage once every other week for 8 weeks. Thirty minutes after each AT2220 oral administration, rhGAA (20 mg/kg) w

NIAID Data Ecosystem80

Trpv4-KO

基因功能研究

疾病模型构建

由国家遗传工程小鼠资源库合作共建单位江苏集萃药康生物科技有限公司利用基因编辑技术，自主研发，供应，保存。应用领域为：无效等位基因的纯合子表现出异常的触觉/伤害感受和迟发性听力损失。不同无效等位基因的纯合子显示膀胱排尿受损，触觉/伤害感受异常，渗透调节和血管舒张，高眼压但没有听力或前庭缺陷。

中国科技资源共享网60

Development of a Transformation System for Chlamydia trachomatis: Restoration of Glycogen Biosynthesis by Acquisition of a Plasmid Shuttle Vector

病原体遗传转化

糖原代谢

Chlamydia trachomatis remains one of the few major human pathogens for which there is no transformation system. C. trachomatis has a unique obligate intracellular developmental cycle. The extracellula

Figshare2016-01-18 更新30

Chromosomal Manipulation by Site-Specific Recombinases and Fluorescent Protein-Based Vectors

基因编辑技术

疾病模型构建

Feasibility of chromosomal manipulation in mammalian cells was first reported 15 years ago. Although this technique is useful for precise understanding of gene regulation in the chromosomal context, a

NIAID Data Ecosystem70

Expression data from the mouse liver with constitutively active NF-kB

疾病模型构建

基因表达谱分析

Expression data from the mouse liver with constitutively active NF-kB

ChEBI2012-03-31 更新30