Luminal and mucosal microbiota in the duodenum and jejunum of Eimeria acervulina-infected and control broiler chickens

The aim of this study was to determine the effect of Eimeria acervulina infection on the luminal and mucosal microbiota in the duodenum and jejunum of broiler chickens at multiple time points during infection. The study demonstrates that luminal and mucosal bacterial populations differ in the duodenum and jejunum, making it important to understand both populations. Infections may have shorter or longer-term effects on microbiota diversity depending on luminal/mucosal and GIT region. Infection may also influence relative abundances of SCFA-producing bacteria in infected birds.

本研究旨在明确堆型艾美耳球虫（Eimeria acervulina）感染对肉仔鸡十二指肠与空肠腔内及黏膜微生物群的影响，实验覆盖感染过程中的多个时间节点。本研究证实，肉仔鸡十二指肠与空肠内的腔源性与黏膜源性细菌群落存在显著差异，因此同时解析这两类菌群具有重要研究价值。感染对微生物群多样性的影响可表现为短期或长期效应，具体取决于菌群所处的腔/黏膜位置以及胃肠道（Gastrointestinal Tract, GIT）区域。此外，感染还可影响感染肉仔鸡中产短链脂肪酸（Short-Chain Fatty Acid, SCFA）细菌的相对丰度。