1st C+S-DG. Mus musculus

C + S: Context + Shock. Young male C57BL/6J mice were exposed to a contextual fear conditioning paradigm that consisted of: Placement into a novel spatial context for 2 min. After 2 min, a 1 sec (0.5 mA) shock was administered through a floor grid. The 2 min-1 sec shock paradigm was repeated for a total of 3 shocks. 1 min after the last shock, animals were removed to their homecage. RNA was extracted was extracted 1hr, 2hr, 4hr, and 6hr after the last shock treatment. Keywords: time-course

C+S：情境（Context）+ 电击（Shock）。年轻雄性C57BL/6J小鼠接受情境恐惧条件化范式（contextual fear conditioning paradigm）处理，具体实验流程为：将小鼠置于全新空间环境中2分钟；2分钟后，通过地板网格施加1秒、0.5毫安的电击。上述“2分钟环境暴露+1秒电击”的操作循环共计重复3次。末次电击结束1分钟后，将小鼠转移至饲养笼。于末次电击处理后的1小时、2小时、4小时及6小时四个时间点提取RNA。关键词：时间进程（time-course）。