Long noncoding RNA TCONS_00027385 acts as a miR-874-5p sponge to suppress the progression of prostate cancer through regulating ASCC2 expression. Long noncoding RNA TCONS_00027385 acts as a miR-874-5p sponge to suppress the progression of prostate cancer through regulating ASCC2 expression

Coal tar pitch (CTP) is a byproduct of cooking process which is used in making coatings, corrosion protection materials, and electrode. and it has been verified that Coal tar pitch extract (CTPE) constitutes polycyclic aromatic hydrocarbons (PAHs) (87.91%) and monocyclic aromatic hydrocarbons, heterocyclic compounds and alkenes (the remaining total is 12.09%) using gas chromatography/mass spectrometry (GC/MS). In this study, we determine the lncRNA expression profile in CTPE group and control group. The key lncRNAs were screen out by using microarray analysis in defferent group. The experiment is divided into two groups: 22RV1 cells as control group, 22RV1 cells induced with Robustanoids A. then perform lncRNAs chips by Arraystar Human lncRNAs chip (Arraystar). Overall design: Jianxin,Han

煤焦油沥青（Coal tar pitch, CTP）是蒸煮工艺的副产物，可用于制备涂料、防腐材料及电极。经气相色谱-质谱联用法（Gas Chromatography/Mass Spectrometry, GC/MS）检测证实，煤焦油沥青提取物（Coal tar pitch extract, CTPE）的组分包含87.91%的多环芳烃（Polycyclic Aromatic Hydrocarbons, PAHs），以及单环芳烃、杂环化合物与烯烃（剩余总占比为12.09%）。本研究旨在检测CTPE处理组与对照组的长链非编码RNA（long non-coding RNA, lncRNA）表达谱，并通过芯片分析筛选两组间的关键差异lncRNA。本实验分为两组：以22RV1细胞作为对照组，将22RV1细胞经Robustanoids A诱导处理；随后采用Arraystar人类长链非编码RNA芯片（Arraystar Human lncRNAs Chip, Arraystar）开展lncRNA芯片检测。实验设计：韩建鑫（Jianxin, Han）