Assessment of patients with Covid-19 hospitalized in southern Santa Catarina

Abstract INTRODUCTION: Coronavirus disease 2019 (COVID-19), a potentially fatal disease, is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The number of cases has increased rapidly, but information on the clinical characteristics remains limited. METHODS: Cohort study. We collected and analyzed epidemiological, demographic, and clinical data of critically and noncritically ill patients and compared the outcomes. RESULTS: The mean age of hospitalized patients with COVID-19 was 54 years (standard deviation 16.9; 53.8% men), 29% required ICU admission, and 18.6% died. CONCLUSIONS: The main risk factors for ICU admission were age over 60 years, obesity, and preexisting chronic lung diseases.

引言：新型冠状病毒肺炎（Coronavirus disease 2019, COVID-19）是一种可危及生命的疾病，由严重急性呼吸综合征冠状病毒2型（severe acute respiratory syndrome coronavirus-2, SARS-CoV-2）引发。当前确诊病例数快速攀升，但有关该疾病临床特征的相关信息仍较为有限。
研究方法：本研究为队列研究。我们收集并分析了重症与非重症新冠患者的流行病学、人口统计学及临床数据，并对其临床转归进行比较。
研究结果：住院新冠患者的平均年龄为54岁（标准差16.9；男性占比53.8%），其中29%的患者需入住重症监护室（intensive care unit, ICU），18.6%的患者死亡。
研究结论：需入住重症监护室的主要危险因素包括年龄超过60岁、肥胖以及既往慢性肺部疾病。