Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT019

Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT019 Descriptor: (3R)-3-{3-[(1-benzofuran-3-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... Authors: Fieulaine, S, Giglione, C, Meinnel, T. Deposit date: 2016-04-19 Release date: 2016-11-30 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016无乳链球菌（Streptococcus agalactiae）来源的2型肽脱甲酰基酶（Peptide Deformylase, PDF）与抑制剂AT019形成复合物的晶体结构。配体描述：(3R)-3-{3-[(1-苯并呋喃-3-基)甲基]-1,2,4-噁二唑-5-基}-4-环戊基-N-羟基丁酰胺、乙酸根离子（ACETATE ION）、咪唑（IMIDAZOLE）…… 作者：Fieulaine S、Giglione C、Meinnel T 入库日期：2016-04-19 发布日期：2016-11-30 最后修改日期：2024-01-10 测定方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.4埃（Å）） 引用文献：《科学报告（Sci Rep）》2016年第6卷，论文题为《用于合理设计并验证新型活性化合物的独特肽脱甲酰基酶研究平台》