CIL:27858

One of the principal challenges in counting or segmenting nuclei is dealing with clustered nuclei. To help assess algorithms' performance in this regard, this synthetic image set consists of five subsets with increasing degree of clustering. Five subsets of 20 images each are provided. Each image contains 300 objects, but the objects overlap and cluster with overlap probability ranging from 0.0 to 0.6, and can be found with CIL 27833, 27853, 28754, 28734, and 28714, respectively. This image set has 0.15 probability overlap. The images were generated with the SIMCEP (http://www.cs.tut.fi/sgn/csb/simcep/tool.html) simulating platform for fluorescent cell population images (Lehmussola et al., IEEE T. Med. Imaging, 2007 and Lehmussola et al., P. IEEE, 2008). Ground truth for foreground/background segmentation are available as binary images as the second image in the tiff image stack. Recommended citation We used the Synthetic 1 image set (Ruusuvuori et al., in Proc. of the 16th European Signal Processing Conference (EUSIPCO-2008), 2008), available from the Broad Bioimage Benchmark Collection (www.broad.mit.edu/bbbc).

细胞核计数与分割任务的核心挑战之一，在于如何处理聚集粘连的细胞核。为辅助评估算法在该场景下的性能表现，本合成图像集共包含五个子集，各子集的细胞核聚集粘连程度依次递增。本数据集共提供5个子集，每个子集包含20张图像。每张图像内预设300个细胞核目标，目标间的重叠粘连概率范围为0.0至0.6，五个子集分别对应CIL 27833、27853、28754、28734与28714编号。该图像集的目标重叠概率为0.15。本数据集采用SIMCEP（http://www.cs.tut.fi/sgn/csb/simcep/tool.html）荧光细胞群体图像仿真平台生成（参考文献：Lehmussola等，《IEEE医学成像汇刊》，2007年；Lehmussola等，《IEEE汇刊》，2008年）。前景/背景分割的真值标签以二值图像形式提供，位于TIFF图像堆栈的第二帧位置。推荐引用格式：本合成1号图像集源自Broad生物图像基准数据集集合（Broad Bioimage Benchmark Collection，网址：www.broad.mit.edu/bbbc），其引用参考为Ruusuvuori等，收录于第16届欧洲信号处理大会（EUSIPCO-2008）论文集，2008年。