Levamisole on the biochemical and hematological responses to parasitism by monogenoids in dog snapper

ABSTRACT: The response of biochemical and hematological parameters were analyzed in dog snapper (Lutjanus jocu) grown in net cages, as well as for the specimens kept in the laboratory during an infestation by Neobenedenia melleni, and after treatment with freshwater bath and injectable application of levamisole. Significant changes were observed in N. melleni parasitized individuals, characterized by increased glucose and lactate levels, as well as a significant fish hematocrit reduction and leukocyte increase. Treatment with freshwater baths, concomitant with injectable levamisole application, showed therapeutic efficacy in several parameters after 14 days of treatment.

摘要：本研究分析了网箱养殖的犬笛鲷（dog snapper, Lutjanus jocu），以及实验室暂养且感染梅氏新本尼登虫（Neobenedenia melleni）、并经淡水浸泡与左旋咪唑（levamisole）注射给药治疗的标本的生化与血液学指标变化情况。研究观察到，感染梅氏新本尼登虫的个体出现显著异常：血糖与乳酸水平升高，血细胞比容显著降低，白细胞数量增多。联合使用淡水浸泡与左旋咪唑注射给药的治疗方案，在实施14天后对多项指标展现出治疗功效。