SH1426587.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE 为基于DNA的物种假说（Species Hypotheses，简称SH）的界定、识别、传播与相关研究提供了统一的操作框架。研究团队通过应用一系列动态距离阈值（0.5%至3.0%），将国际核苷酸序列数据库中的全部真菌ITS序列聚类至近似物种级别的单元。所有物种假说均会被赋予以数字对象标识符（DOI）为形式的唯一且稳定的专属名称，其分类学与生态学注释信息将通过分布式的网络第三方注释工作完成权威核验。系统会尽可能结合物种假说所包含的全部序列的鉴定结果，将其关联至对应的分类单元名称及其所属的分类层级（如门、纲、目等），并为每个物种假说选取一条经自动或人工指定的序列作为代表序列。此类代表序列已通过https://unite.ut.ee/repository.php 公开发布，可供科研群体用于本地序列相似性检索、新一代测序分析流程等科研场景。随着公共真菌ITS序列数据体量的持续增长，该系统与配套数据集将自动完成更新。