Host interaction candidate genes with unknown function.

Genes annotated as hypothetical (A) or encoding a domain of unknown function (B) meeting significance criteria in at least one host site were analyzed to identify similarities with other Neisseria species. ORFs are listed with results of tradis.comparison.R analysis. Genes with similarity to those encoded by either human commensal, pathogen, or animal commensal species are color coded according to similarity key. Percent identity is reported from KEGG database GFIT SSDB searches by N. musculi Genbank locus tag. Species abbreviations are shown according to KEGG nomenclature for strain designation. Nme, Neisseria meningitidis MC58; Nel, Neisseria elongata sups. glycolitica ATCC29315; Ngo, Neisseria gonorrhoeae FA1090; Nla, Neisseria lactamica 02–06; Nsi, Neisseria mucosa FDAARGOS; Nfv, Neisseria flavescens ATCC 13120; Ncz, Neisseria cinerea NCTC10294; Nci, Neisseria canis NCTC10296; Nbc, Neisseria baciliformis DSM 233383; Nmj, Neisseria mucosa ATCC 19696; Nani, Neisseria animaloris NCTC12227; Nsf, Neisseria subflava ATCC 49275; Nzo, Neisseria zoodegmatis NCTC12230; Nsg, Neisseria shayeganii DSM22244; Nsc, Neisseria sicca NS20201025; Nwd, Neisseria wadsworthii DSM22245; Nwe, Neisseria weaveri NCTC13585. (XLSX)

将至少在一个宿主位点满足显著性筛选标准的、被注释为假想蛋白编码基因（hypothetical protein）或编码功能未知结构域（domain of unknown function）的基因进行分析，以鉴定其与其他奈瑟菌属（Neisseria）物种的同源序列相似性。开放阅读框（Open Reading Frame, ORF）将附带tradis.comparison.R分析的结果一并列出。与人类共生菌、致病菌或动物共生菌编码的基因存在同源相似性的基因，将根据相似性标记进行颜色编码标注。序列一致性百分比由小鼠奈瑟菌（Neisseria musculi）的Genbank基因座标签通过KEGG数据库GFIT SSDB搜索获得。物种缩写将按照KEGG命名法进行菌株标注：
Nme：脑膜炎奈瑟菌（Neisseria meningitidis）MC58；
Nel：延加奈瑟菌糖酵解亚种（Neisseria elongata sups. glycolitica）ATCC29315；
Ngo：淋病奈瑟菌（Neisseria gonorrhoeae）FA1090；
Nla：乳酸奈瑟菌（Neisseria lactamica）02–06；
Nsi：黏膜奈瑟菌（Neisseria mucosa）FDAARGOS；
Nfv：微黄奈瑟菌（Neisseria flavescens）ATCC 13120；
Ncz：灰奈瑟菌（Neisseria cinerea）NCTC10294；
Nci：犬奈瑟菌（Neisseria canis）NCTC10296；
Nbc：杆状奈瑟菌（Neisseria baciliformis）DSM 233383；
Nmj：黏膜奈瑟菌（Neisseria mucosa）ATCC 19696；
Nani：动物奈瑟菌（Neisseria animaloris）NCTC12227；
Nsf：亚黄奈瑟菌（Neisseria subflava）ATCC 49275；
Nzo：兽疫奈瑟菌（Neisseria zoodegmatis）NCTC12230；
Nsg：谢加奈瑟菌（Neisseria shayeganii）DSM22244；
Nsc：干燥奈瑟菌（Neisseria sicca）NS20201025；
Nwd：沃兹沃思奈瑟菌（Neisseria wadsworthii）DSM22245；
Nwe：韦弗奈瑟菌（Neisseria weaveri）NCTC13585。
（XLSX格式）