the dynamics and evolutionary trajectories of resistance in a meropenem killing assay

We serially passaged a P. aeruginosa reference strain PA14 in a meropenem killing assay to analyze the dynamics and evolutionary trajectories of resistance.我们在美罗培南杀菌试验中对铜绿假单胞菌（Pseudomonas aeruginosa）参考菌株PA14进行连续传代培养，以解析其耐药性的动态变化与进化轨迹。