Remodeling rate parameters from six independent experiments.

Inferred remodeling rate parameters from six independent experiments. A “-” indicates unmodeled reactions either due to missing species or low flux in the experiment. The sn1 18:0 to 18:1 rate parameters inferred from two precursor experiments are similar: 0.0673 and 0.07 for the respective 18:0-18:1 and 18:0-22:6 experiments. The sn1 rate parameters of the first row have ratios 1:0.19:029, similar to ratios in the second row 1:0.18:- and third row 1:0.26:0.24. This indicates that the relative reacylation rates of 18:1, 18:0, and 16:1 are consistently ranked across experiments. Likewise, by comparing values within a column, we can determine relative deacylation rates, i.e. 14:118:314:0 at ratios 6.58:3:1 at the sn1 position. Analogous behavior was also observed for the sn2 position (See Supporting Information S1 for details).从6项独立实验中推导得到脂质重塑速率参数。符号“-”表示因对应物种缺失或实验中通量过低而未被建模的反应。从两项前体实验中推导得到的sn1位点18:0向18:1转化的速率参数相近：对应18:0-18:1与18:0-22:6实验的参数分别为0.0673与0.07。第一行的sn1速率参数比值为1:0.19:0.29，与第二行的1:0.18:-及第三行的1:0.26:0.24比值相近，这表明18:1、18:0与16:1的相对再酰化速率在不同实验中保持一致的排序。同理，通过比较列内数值可得到相对脱酰化速率：即sn1位点上14:1、18:3与14:0的比值为6.58:3:1。sn2位点也观察到了类似的行为（详细信息参见辅助材料S1）。