INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1745658474

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1745658474 Descriptor: 2-(trifluoromethyl)pyrimidine-5-carboxamide, DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA 分析组提交数据集——SHIP1的磷酸酶结构域与C2结构域结合Z1745658474的晶体结构。配体描述：2-(三氟甲基)嘧啶-5-甲酰胺、二甲基亚砜（Dimethyl Sulfoxide）、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1。作者：Bradshaw, W.J.、Newman, J.A.、von Delft, F.、Arrowsmith, C.H.、Edwards, A.M.、Bountra, C.、Gileadi, O.。提交日期：2020-10-30；发布日期：2020-11-11；最后修改日期：2026-02-18。实验方法：X射线衍射（1.55 Å）。引用文献：《通过SHIP1与SHIP2的C2结构域调控肌醇5-磷酸酶活性》，《Structure》，2024年。