TRPV3 突变小鼠毛发外观、组织学检测和电镜检测结果

数据采集时间为2017-2020年，数据在北京大学第一医院和中国医学科学院皮肤病医院采集。此图集图谱来源于项目产生的原始数据，含1条记录。成功构建了Olmsted综合征少毛症的小鼠模型，并进一步通过对不同年龄的小鼠进行苏木-伊红染色、扫描电子显微镜、透射电子显微镜等技术，明确了TRPV3功能增强型突变小鼠的毛发结构异常，为进一步探究此小鼠中原发性的病理改变提供线索，可供科研、发表论文、成果转化而使用。The data were collected between 2017 and 2020 at Peking University First Hospital and the Hospital for Skin Diseases, Chinese Academy of Medical Sciences. This atlas dataset is derived from the raw data generated by the project and contains 1 record. A mouse model of hypotrichosis associated with Olmsted syndrome was successfully established. Subsequently, hematoxylin-eosin staining, scanning electron microscopy, transmission electron microscopy and other technical approaches were applied to mice at different ages, and the abnormal hair structure of TRPV3 gain-of-function mutant mice was identified. This work provides clues for further exploration of the primary pathological changes in these mice, and the dataset is available for scientific research, paper publication and achievement transformation.