Table_1_Generalized Anxiety Disorder and Its Associated Factors Among Pregnant Women During COVID-19 at Public Health Facilities of East Gojjam Zone, 2020: A Multi-Center Cross-Sectional Study.DOCX

IntroductionPregnant women suffer from varying levels of generalized anxiety disorder that result in poor obstetrical outcomes. Therefore, this study aimed to assess the prevalence and factors associated with generalized anxiety disorder among pregnant women attending antenatal care during COVID-19 at the public health facilities in the east Gojjam zone.
MethodsA health facility-based cross-sectional study was conducted, from 1–30 December 2020. A total of 847 pregnant women were included in the study using a systematic random sampling technique. We used an interviewer-administered questionnaire to collect the data. Bivariate and multivariable logistic regression was used to identify factors associated with the outcome variable. Statistical significance was determined using a p-value < 0.05 and a 95% confidence level.
ResultsThe prevalence of generalized anxiety disorder was 43.7%, with a 95% CI (40.28–47.12). Having <3 the number of children (AOR: 1.53; 95% CI: 1.11–2.13, having a negative attitude about COVID (AOR: 1.47; 95% CI: 1.07–2.02 and having a high-risk perception about COVID (AOR: 1.86; 95% CI: 1.34–2.57 were factors significantly associated with generalized anxiety disorder.
ConclusionsThe study found that the prevalence of generalized anxiety disorder was high. Having less than three children, having a negative attitude, and having a high-risk perception of COVID were independent risk factors of generalized anxiety disorder. Appropriate interventions should be considered to address generalized anxiety disorder during the pandemic.

引言 孕妇群体普遍存在不同程度的广泛性焦虑障碍（Generalized Anxiety Disorder），该病症可引发不良妊娠结局。本研究旨在评估东戈贾姆地区公立医疗机构内，新冠疫情（COVID-19）期间接受产前保健（Antenatal Care）的孕妇中广泛性焦虑障碍的患病率及其相关影响因素。
方法 本研究于2020年12月1日至30日开展，为基于医疗机构的横断面研究。采用系统随机抽样（Systematic Random Sampling）方法，最终纳入847名孕妇作为研究对象。通过访谈式问卷收集研究数据，采用双变量及多变量逻辑回归（Logistic Regression）分析筛选与结局变量相关的影响因素。以P值<0.05且95%置信水平作为统计学显著性判定标准。
结果 广泛性焦虑障碍的患病率为43.7%，95%置信区间（Confidence Interval, CI）为40.28~47.12。生育子女数少于3名（调整后比值比Adjusted Odds Ratio, AOR：1.53；95%CI：1.11~2.13）、对新冠疫情持负面态度（AOR：1.47；95%CI：1.07~2.02）以及对新冠疫情存在高风险认知（AOR：1.86；95%CI：1.34~2.57）均为与广泛性焦虑障碍显著相关的影响因素。
结论 本研究显示，孕妇群体中广泛性焦虑障碍的患病率处于较高水平。生育子女数少于3名、对新冠疫情持负面态度以及对新冠疫情存在高风险认知均为广泛性焦虑障碍的独立危险因素。建议在新冠疫情大流行期间采取针对性干预措施，以缓解孕妇的广泛性焦虑障碍症状。