Additional file 2 of From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models
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Additional file 2: Table S1. Potentially actionable copy number variants. Table S2. Germline pathogenic variants. Table S3. Functional roles of genes harboring germline pathogenic variants. Table S4. Somatic pathogenic single nucleotide variants and insertions/deletions. Table S5. Somatic copy number variants (CN=0 and CN>10). Table 6. Potentially therapeutically targetable somatic alterations. Table S7. Percentage of conserved somatic variants among patient's tumors and PDX/CPDX and 3D models.
附加文件2:表S1. 潜在可操作拷贝数变异。表S2. 生殖系致病性变异。表S3. 携带生殖系致病性变异的基因的功能作用。表S4. 体细胞致病性单核苷酸变异及插入/缺失。表S5. 体细胞拷贝数变异(CN=0 且 CN>10)。表6. 潜在可治疗靶向的体细胞改变。表S7. 患者肿瘤、PDX/CPDX及3D模型中保守体细胞变异的占比。
提供机构:
Mura, Rossella; Pastorino, Fabio; Fruci, Doriana; Capasso, Mario; Calarco, Enzo; Rabusin, Marco; Aveic, Sanja; Coccia, Paola; Cilli, Michele; Sebastiani, Enrico; Luksch, Roberto; Gaggero, Gabriele; Cellini, Monica; Corrias, Maria V.; Vellone, Valerio G.; Amoroso, Loredana; Conte, Massimo; Tondo, Annalisa; Cantalupo, Sueva; Ponzoni, Mirco; Giusto, Elena; Garaventa, Alberto; Perri, Patrizia; De Leonardis, Francesco; Mazzocco, Katia; Bensa, Veronica; Avitabile, Marianna; Lasorsa, Vito A.; Iolascon, Achille; Quattrone, Alessandro; Sementa, Angela R.; Cafferata, Barbara; Ciampi, Eleonora; Brignole, Chiara
创建时间:
2024-08-14



