Additional file 2 of OXPHOS mediators in acute myeloid leukemia patients: Prognostic biomarkers and therapeutic targets for personalized medicine

Supplementary Material 2: Figure S1. Area under the curve (AUC) of receiver operating characteristic (ROC) curves of the indicated genes in biospecimens obtained from AML patients (BeatAML.2 cBioportal dataset (OHSU, Cancer Cell, 2022). A-F) ROC curves and AUC of NADH:ubiquinone oxidoreductase subunit A6 (NDUFA6) (A), succinate dehydrogenase complex flavoprotein subunit A (SDHA) (B), solute carrier family 25 member 12 (SLC25A12) (C), electron transfer flavoprotein subunit beta (ETFB) (D), carnitine palmitoyltransferase 1A (CPT1A) (E) and glutathione peroxidase 4 (GPX4) (F) at the indicated time points of overall survival.

补充材料2：图S1。急性髓系白血病（Acute Myeloid Leukemia, AML）患者来源的生物样本中，指定基因的受试者工作特征（Receiver Operating Characteristic, ROC）曲线下面积（Area Under the Curve, AUC），数据来自BeatAML.2 cBioPortal数据集（俄勒冈健康与科学大学（OHSU），《癌细胞》（Cancer Cell），2022年）。A~F分别为烟酰胺腺嘌呤二核苷酸：泛醌氧化还原酶亚基A6（NADH:ubiquinone oxidoreductase subunit A6, NDUFA6）（A）、琥珀酸脱氢酶复合物黄素蛋白亚基A（succinate dehydrogenase complex flavoprotein subunit A, SDHA）（B）、溶质载体家族25成员12（solute carrier family 25 member 12, SLC25A12）（C）、电子转移黄素蛋白亚基β（electron transfer flavoprotein subunit beta, ETFB）（D）、肉碱棕榈酰转移酶1A（carnitine palmitoyltransferase 1A, CPT1A）（E）以及谷胱甘肽过氧化物酶4（glutathione peroxidase 4, GPX4）（F）在总生存期指定时间点的ROC曲线与对应AUC值。