CLINICAL AND FUNCTIONAL ANALYSIS AFTER TOTAL KNEE ARTHROPLASTY

ABSTRACT Osteoarthritis is a major cause of disability worldwide. Objective: To evaluate the effects of Total Knee Arthroplasty of subjects with knee osteoarthritis by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC ). Methods: Prospective, non-randomized study with convenience sampling. We included subjects with knee osteoarthritis with indication for surgical treatment. We used WOMAC to evaluate the level of pain, joint stiffness, physical activity, and quality of life in the preoperative and postoperative phase six months after unilateral surgery. We compared WOMAC to the factors age, gender, Body Mass Index and the type of angular deformity of the knee. Results: In total, we analyzed 58 patients with significant improvements in pain relief, joint stiffness, level of physical activity, and quality of life six months after total knee arthroplasty according to WOMAC. Conclusion: Total knee arthroplasty showed positive effects on the quality of life of patients with knee osteoarthritis. Level of Evidence II, Cohort Study.

摘要 骨关节炎（Osteoarthritis）是全球范围内导致残疾的主要病因。目的：采用西安大略和麦克马斯特大学骨关节炎指数（Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC）评估全膝关节置换术（Total Knee Arthroplasty）对膝关节骨关节炎患者的治疗效果。方法：本研究为采用便利抽样的前瞻性非随机研究，纳入符合手术治疗指征的膝关节骨关节炎患者。分别于术前及单侧全膝关节置换术后6个月，采用WOMAC指数评估患者的疼痛程度、关节僵硬情况、肢体活动水平与生活质量，并将WOMAC评分与患者年龄、性别、体重指数（Body Mass Index, BMI）及膝关节成角畸形类型进行对比分析。结果：本研究共分析58例患者，经全膝关节置换术后6个月，依据WOMAC指数评估结果显示，患者的疼痛缓解、关节僵硬改善、肢体活动水平提升及生活质量均获得显著改善。结论：全膝关节置换术可对膝关节骨关节炎患者的生活质量产生积极影响。本研究证据等级为Ⅱ级，属于队列研究（Cohort Study）。