We present evidence of mechanistically diverse allosteric relays converging on a few peptidyltransferase center (PTC) nucleotides, and propose a general model of antibiotic resistance mediated by thes

NIAID Data Ecosystem10

Ciprofloxacin tolerance and resistance in E. coli

抗生素耐受性检测

细菌耐药性机制

Antibiotic screens typically rely on growth inhibition to characterize compound bioactivity â an approach that is unable to assess the bactericidal activity of antibiotics against bacteria in drug-t

NIAID Data Ecosystem00

ReGAIN Supplemental Figures

细菌耐药性机制

基因共现网络分析

The rampant rise of multidrug-resistant (MDR) bacterial pathogens poses a serious health threat, necessitating innovative tools to unravel the complex genetic underpinnings of antimicrobial resistance

Figshare2025-05-08 更新10

Table_2_Characterization and Identification of a novel chromosome-encoded metallo-β-lactamase WUS-1 in Myroides albus P34.DOCX

新型β-内酰胺酶鉴定

细菌耐药性机制

In this study, we identified and characterized a novel chromosomally-encoded class B metallo-β-lactamase (MBL) gene designated blaWUS-1 in a carbapenem-resistant isolate Myroides albus P34 isolated fr

NIAID Data Ecosystem10

CDD-1 beta-lactamase in imidazole/MPD 6 minute avibactam complex

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