Km values of the unwinding of four DNA substrates by WRN and BLM helicases.

The listed Km values were determined as described under ‘Materials and Methods’ and in the legend to Fig. 2.aN – Number of independent determinations of each Km value.bND – Not determined; the extent of unwinding of bubble DNA by BLM (Table 1) was too low to permit determination of a reliable Km value.所列的Km值均按照《材料与方法》章节及图2图例中的描述方法测定得到。 aN — 每个Km值的独立测定次数。 bND — 未测定；BLM对气泡DNA的解旋程度（见表1）过低，无法获得可靠的Km值。