Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine

Protein Data Bank Japan2023-10-18 更新2026-03-21 收录

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Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 7-({3-[2-(6-aminopyridin-2-yl)ethyl]phenoxy}methyl)quinolin-2-amine, ... Authors: Li, H, Poulos, T.L. Deposit date: 2021-03-22 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.957 Å) Cite: Inhibition of bacterial nitric oxide synthase as an antimicrobial tool in fighting some antibiotic-resistant pathogens To be published

人源内皮型一氧化氮合酶（endothelial nitric oxide synthase）血红素结构域与7-((3-(3-氨基苯乙基)苯氧基)甲基)喹啉-2-胺的复合物结构共结晶组分：2-[双(2-羟乙基)氨基]-2-(羟甲基)丙烷-1,3-二醇、5,6,7,8-四氢生物蝶呤（tetrahydrobiopterin）、7-({3-[2-(6-氨基吡啶-2-基)乙基]苯氧基}甲基)喹啉-2-胺等作者：Li, H、Poulos, T.L. 提交日期：2021-03-22 发布日期：2022-03-30 最后修改日期：2023-10-18 实验方法：X射线衍射（分辨率1.957埃）引用文献：《抑制细菌一氧化氮合酶作为对抗部分抗生素耐药病原菌的抗菌工具》（待发表）

创建时间：

2021-03-22