Distribution of the HPV16 variants within different grades of cervical lesions.

aU, unknown diagnosis; NC, normal cytology; ASCUS, atypical squamous cells of undetermined significance; LSIL, low grade squamous intraepithelial neoplasia; HSIL, high grade squamous intraepithelial neoplasia.bvariant names according to the recently proposed nomenclature [16]; E-G350 other, all other variants containing 350G and other variations but found in less than 5 samples each; E-r other, all other variants containing 350T with other variations.cNo., number of samples.dthis was statistically significant in comparison to E1 reference E-r (p = 0.0227), E1 reference E-G350 (p = 0.0326), E1 reference subtotal E (p = 0.0128) and subtotal E1 reference samples (p = 0.0143).ethis was statistically significant in comparison to E1 reference subtotal E (p = 0.0452) and borderline significant in comparison with subtotal E1 reference samples (p = 0.0503).a aU：未知诊断（unknown diagnosis）；NC：细胞学正常（normal cytology）；ASCUS：意义不明的非典型鳞状细胞（atypical squamous cells of undetermined significance）；LSIL：低级别鳞状上皮内病变（low grade squamous intraepithelial neoplasia）；HSIL：高级别鳞状上皮内病变（high grade squamous intraepithelial neoplasia）。 b 变体命名依据最新提出的命名体系[16]；E-G350 other：所有其余携带350G突变且存在其他变异，但单类变异的样本量均少于5例的变体；E-r other：所有其余携带350T突变且存在其他变异的变体。 c No.：样本数量（number of samples）。 d 该结果与E1参照株E-r（p=0.0227）、E1参照株E-G350（p=0.0326）、E1参照亚组E（p=0.0128）以及亚组E1参照样本（p=0.0143）相比，差异具有统计学显著性。 e 该结果与E1参照亚组E相比差异具有统计学显著性（p=0.0452），与亚组E1参照样本相比则呈临界显著性差异（p=0.0503）。