Trauma patients data (2016-2022)

This study aimed to assess the predictive value of lactate-to-albumin ratio (LAR) for in-hospital mortality and massive transfusion (MT) in severe trauma cases. This retrospective, observational, single-center study included patients who presented to a trauma center between 2016 and 2022. The primary outcome was in-hospital mortality, and the secondary outcome was MT. Logistic regression analysis was performed to determine whether LAR was an independent risk factor. The area under the receiver operating characteristic (AUROC) curve was calculated to evaluate the predictive value of LAR. In total, 5,304 patients were included. Logistic regression analysis identified LAR as an independent risk factor for in-hospital mortality. The AUROCs for predicting in-hospital mortality using LAR, Injury Severity Score (ISS), and Shock Index (SI) were 0.74 (95% confidence interval [CI], 0.73–0.75), 0.78 (95% CI, 0.77–0.779), and 0.51 (95% CI, 0.49–0.52), respectively. LAR was statistically significant compared with SI (p本研究旨在评估乳酸白蛋白比值（lactate-to-albumin ratio, LAR）对严重创伤患者院内死亡率与大量输血（massive transfusion, MT）的预测价值。本研究为回顾性观察性单中心研究，纳入2016至2022年期间就诊于创伤中心的患者。主要结局指标为院内死亡率，次要结局指标为大量输血。采用Logistic回归分析明确乳酸白蛋白比值是否为独立危险因素。计算受试者工作特征曲线下面积（area under the receiver operating characteristic, AUROC）以评估乳酸白蛋白比值的预测价值。本研究共纳入5304例患者。Logistic回归分析显示，乳酸白蛋白比值为院内死亡率的独立危险因素。利用乳酸白蛋白比值、损伤严重度评分（Injury Severity Score, ISS）及休克指数（Shock Index, SI）预测院内死亡率的AUROC分别为0.74（95%置信区间[CI], 0.73–0.75）、0.78（95% CI, 0.77–0.779）及0.51（95% CI, 0.49–0.52）。与休克指数相比，乳酸白蛋白比值的差异具有统计学意义（p