Paralog Variant Classification And Scoring

<em>Para_zscore </em>data Input data, annotation of all hg19 missense variants, score for every gene having a paralog in the human genes. This dataset is a supplement for the publication Lal. et al. Information on the files, scripts to generate and use the <em>para_zscore</em> are available under https://git-r3lab.uni.lu/genomeanalysis/paralogs. Version 840860 changes: The family 225.para.1 changed because of a problem with the multiple alignment of TTN. TTN is now not part of the family anymore. Updated files with the according changes for this family and family members have been added, plus a new track that can directly plugged into Annovar has been added.Para_zscore 数据集 本数据集涵盖人类参考基因组hg19的所有错义变异注释信息，以及人类基因组中存在旁系同源基因的每个基因的评分，为Lal等人发表的学术论文的补充数据。 有关该数据集的文件、生成与使用脚本的详细信息，可通过以下链接获取：https://git-r3lab.uni.lu/genomeanalysis/paralogs. 版本840860更新内容如下： 家族225.para.1因TTN的多序列比对出现问题而发生变更，TTN现已不再隶属于该家族；已补充上传适配该家族及其成员变更的更新文件，并新增了可直接接入Annovar的全新基因组注释轨道。