Table_1_Neurobehavioral Symptoms in Community-Dwelling Adults With and Without Chronic Traumatic Brain Injury: Differences by Age, Gender, Education, and Health Condition.DOCX

Neurobehavioral symptoms after Traumatic Brain Injury (TBI) are prevalent, persist for many years, and negatively affect long-term health, function, and quality of life. Symptoms may differ based on age, gender, education, race, ethnicity, and injury severity. To better understand neurobehavioral functioning after TBI, we need a comprehensive picture of emotional, cognitive, and behavioral symptoms in the context of personal factors that may affect these symptoms. We also need to understand the extent to which these symptoms are specific to TBI, shared across other neurological conditions, or attributable to factors outside of the injury itself. We collected neurobehavioral symptoms via the self-reported Behavioral Assessment Screening Tool (BAST) in a National Cohort of English (n = 2,511) and Spanish speaking (n = 350) community-dwelling adults with and without chronic TBI and other neurological and mental health conditions. The primary focus of the present study was to comprehensively describe neurobehavioral symptoms in adults with and without TBI, broken down by gender and health conditions and then further by age group or educational attainment. As expected, participants with TBI reported more symptoms than Healthy Controls. Regardless of condition, women reported more fatigue, while men reported more substance abuse and impulsivity. Hispanic participants reported more neurobehavioral symptoms than non-Hispanic participants did across health conditions, though primarily Spanish-speakers reported fewer symptoms than English-speakers, suggesting that level of acculturation may contribute to symptom reporting. These data provide a comprehensive characterization of neurobehavioral symptoms in adults with TBI and adults without TBI (healthy controls, adults with other neurological conditions, and adults with mental health conditions).

创伤性脑损伤（Traumatic Brain Injury, TBI）后的神经行为症状普遍存在，可持续多年，并对长期健康、功能状态与生活质量造成负面影响。此类症状会因年龄、性别、教育水平、种族、族裔以及损伤严重程度的不同而存在差异。为更深入地理解创伤性脑损伤后的神经行为功能，我们需要在可能影响症状的个人因素背景下，全面掌握情绪、认知与行为症状的整体图景。同时，我们也需要明确这些症状在多大程度上具有创伤性脑损伤特异性、在其他神经系统疾病中是否共通，或是源于损伤本身以外的其他因素。本研究通过自我报告式行为评估筛查量表（Behavioral Assessment Screening Tool, BAST），在一项全国性队列中收集了神经行为症状数据，该队列包含2511名英语使用者与350名西班牙语使用者，均为社区居住成人，涵盖患有与未患有慢性创伤性脑损伤、其他神经系统疾病及精神疾病的人群。本研究的核心目标是全面描述伴或不伴创伤性脑损伤的成人的神经行为症状，并按性别与健康状况进行分层，进一步按年龄组或受教育程度细分。正如预期，创伤性脑损伤患者报告的症状多于健康对照组。无论罹患何种疾病，女性报告的疲劳症状更多，而男性则报告更多物质滥用与冲动症状。在各类健康状况中，西班牙裔参与者报告的神经行为症状多于非西班牙裔参与者；不过西班牙语使用者总体报告的症状少于英语使用者，这提示文化融入程度可能会影响症状报告。本数据集全面刻画了伴创伤性脑损伤成人、未伴创伤性脑损伤成人（包括健康对照者、其他神经系统疾病患者与精神疾病患者）的神经行为症状特征。