COX2 Induction in the Ovarian Epithelium Promotes Cell Survival During Ovulatory Wound Repair

We leverage RNA sequencing to identify the transcriptional changes assocaited with a TGFB1-induced epithelial-mesenchymal transition in the mouse ovarian surface epithelium Overall design: RNA sequencing of mOSE cells treated with 10ng/mL TGFB1 or an untreated control (n=3)本研究利用RNA测序（RNA sequencing）技术，鉴定小鼠卵巢表面上皮（mouse ovarian surface epithelium, mOSE）中由转化生长因子β1（TGFB1）诱导的上皮间质转化（epithelial-mesenchymal transition, EMT）相关的转录组变化。实验设计概述：对经10ng/mL TGFB1处理的mOSE细胞及未处理的对照组细胞进行RNA测序，每组设置3个生物学重复（n=3）。