Lysinibacillus fusiformis strain:Juneja Genome sequencing and assembly. Lysinibacillus fusiformis strain:Juneja

Drosophila melanogaster has served as a model for the study of innate immunity for more than 50 years. However, we still have very limited knowledge of their natural bacterial pathogens. Here we isolate and sequence the genome of Lysinibacillus fusiformis Strain Juneja, which was isolated from a laboratory stock of D. melanogaster. As a Gram-positive bacteria with a unique peptidoglycan, this new strain may provide a unique new model to study pathogen recognition.

黑腹果蝇（Drosophila melanogaster）作为先天免疫研究的经典模式生物已逾五十载。然而，学界对其天然细菌性病原体的认知仍极为有限。本研究从实验室保藏的黑腹果蝇群体中分离得到梭形赖氨酸芽孢杆菌（Lysinibacillus fusiformis）Juneja菌株，并完成了其全基因组测序。作为一种携带独特肽聚糖（peptidoglycan）的革兰氏阳性（Gram-positive）细菌，该新菌株可为病原体识别机制的研究提供全新的独特模型。