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A Virtual Library for Behavioral Performance in Standard Conditions – Experiment 15 Q46 Effect of 8OHDPAT dose (0 0.03125 0.0625 0.125 mg/kg) co-injected with a low dose of QNP (0.125 mg/kg) on the development of sensitization and compulsive checking (batch 1)

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DataCite Commons2025-05-26 更新2025-04-15 收录
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http://gigadb.org/dataset/102286
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资源简介:
Beyond their specific experiment, video records of behavior have future value; for example, as inputs for new experiments or for yet unknown types of analysis of behaviorsimilar to tissue or blood sample banks in life sciences where clinically-derived or otherwise well-described experimental samples are stored to be available for some unknown potential future purpose. <br>Research using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test. From 43 experiments, there are 19,976 such trials that amount to over 2 years of continuous recording. In addition to videos, there are two video-derived raw data objects: XY locomotion coordinates, and plots of animal trajectory. To motivate future use, the three raw data objects are annotated with a general schemaone that abstracts the data records from their particular experiment while providing, at the same time a detailed list of independent variables bearing on behavioral performance. The raw data objects are deposited as 43 datasets but constitute, functionally, a library containing one large dataset. <br>Size and annotation schema give the library high re-use potential: in applications using machine learning techniques, statistical evaluation of subtle factors, simulation of new experiments, or as educational resource. Ultimately, the library can serve both as the seed and the test bed to create a machine searchable virtual library of linked open datasets for behavioral performance in defined conditions.

相较于单次特定实验的局限,行为视频记录具备长期复用价值:例如可作为新实验的输入数据,或用于未来未知的行为分析场景——这与生命科学领域的组织或血液样本库类似:后者会储存临床来源或经过完善描述的实验样本,以备未来潜在的未知研究用途。 本数据集基于强迫症(obsessive-compulsive disorder, OCD)动物模型展开研究,采用标准化实验范式:在大型开放场域中,对每一次测试的大鼠行为进行55分钟的视频录制。本次研究共涉及43项独立实验,累计19976次测试,总连续录制时长超过2年。除原始视频外,数据集还包含两类由视频衍生的原始数据对象:大鼠运动的XY坐标轨迹,以及动物运动路径可视化图。为提升未来复用性,三类原始数据对象均采用通用标注模式(schema)进行标注:该模式既可将数据记录脱离其所属的特定实验进行抽象化处理,同时又能完整列出与行为表现相关的全部自变量细节。原始数据对象以43个独立数据集的形式归档,但从功能层面而言,它们共同构成了一个包含单一大型数据集的资源库。 该数据集库凭借其规模与标注模式,具备极高的复用潜力:可应用于机器学习技术驱动的各类任务、细微影响因素的统计评估、新实验的模拟推演,亦可作为教学资源使用。从长远来看,该资源库既可作为构建可机器检索的关联开放数据集虚拟库的起点,也可作为其测试平台——该虚拟库将收录特定实验条件下的行为表现数据。
提供机构:
GigaScience Database
创建时间:
2022-09-21
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