Epigenome analysis of normal and gastric cardia cancer samples

Genome wide DNA methylation profiling of normal and gastric cardia cancer samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in normal and gastric cardia cancer samples. Samples included 8 normal -gastrica cardia cancer paired tissues. Bisulphite converted DNA from the 16 samples were hybridised to the Illumina Infinium 850k Human Methylation Beadchip

该数据集涵盖正常胃贲门组织与贲门癌样本的全基因组DNA甲基化谱分析结果。研究采用Illumina Infinium 850K人类DNA甲基化微珠芯片（Illumina Infinium 850k Human DNA methylation Beadchip），对正常胃贲门组织与贲门癌样本中约850,000个CpG位点（CpG site）的DNA甲基化谱进行检测。本次实验共纳入8对配对的正常胃贲门组织与贲门癌组织样本，总计16份。将16份样本的亚硫酸氢盐转化DNA（Bisulphite converted DNA）与Illumina Infinium 850K人类DNA甲基化微珠芯片进行杂交。