BAG for Signal transduction, DNA repair, marine & structural glycobiology, bacterial polyketide synthases, starch biosynthesis, regulation o

BAG regrouping small crystallographic teams at Lille, Orléans, Roscoff, Nancy and Marseille. For all projects both SAXS and MX-crystallography studies are
required to cover different aspects and scales of these often multimodular proteins. The projects in Lille concern Type V secretion systems, Sars-Cov proteins,
regulatory networks of signal transduction, starch metabolism (synthesis) and structural glycobiology. In Roscoff the projects concern marine glycobiology
and marine phage proteins, deciphering functions of 'unknown' proteins and PUL assemblages. The projects treated in Orléans are DNA structure and repair,
transcription regulation, molecular mechanisms of oxidative stress; in Nancy the studies concern the regulation and mechanisms of prokaryotic polyketide
syntheses. The subjects of Marseille are SAXS studies of ordered and disordered proteins involved in regulation of CO2 assimilation in microalgae.

BAG整合了位于里尔（Lille）、奥尔良（Orléans）、罗斯科夫（Roscoff）、南希（Nancy）及马赛（Marseille）的小型晶体学研究团队。所有研究项目均需结合小角X射线散射（SAXS）与大分子X射线晶体学（MX-crystallography）技术，以覆盖这类多结构域蛋白的不同研究维度与尺度。其中，里尔团队的研究项目涵盖V型分泌系统（Type V secretion systems）、SARS-CoV蛋白、信号转导调控网络、淀粉代谢（合成）及结构糖生物学；罗斯科夫团队的项目聚焦海洋糖生物学与海洋噬菌体蛋白，旨在解析“未知”蛋白的功能及多糖利用位点（PUL）组装体；奥尔良团队的研究主题包括DNA结构与修复、转录调控及氧化应激的分子机制；南希团队的研究围绕原核生物聚酮合成的调控与机制展开；马赛团队的研究则针对微藻二氧化碳同化调控相关的有序与无序蛋白开展小角X射线散射（SAXS）研究。