Number of metastases on the day of achieving a total tumour mass of 1 kg.

The day of reaching a total tumour mass of 1 kg varies from day 1728 in scenario A to day 1852 in scenario D. By resecting the primary tumour this day can be shifted further into the future. In scenario AR the lethal tumour mass is reached at day 1972 if the primary tumour is resected at day 680 or at day 2018 if the primary tumour is resected at day 620. In scenario BR the tumour mass of 1 kg is no longer reached. The significant differences in the number of metastases between the scenarios where metastases are able to metastasize and the scenarios where they are not are particularly remarkable. The difference between scenario A and B is 3901 metastases and between the scenarios C and D 2093 metastases. In contrast, the day of reaching a total tumour mass of 1 kg was only shifted by 12 or 52 days, respectively, into the future.

肿瘤总质量达到1千克所需的天数，在场景A中为第1728天，场景D中则为第1852天。通过切除原发肿瘤，该时间节点可进一步向后延迟。在场景AR中，若在第680天切除原发肿瘤，则机体将在第1972天达到致死性肿瘤总质量；若在第620天切除原发肿瘤，则该时间节点为第2018天。在场景BR中，机体将不再达到1千克的肿瘤总质量。允许肿瘤发生转移的场景与肿瘤无法发生转移的场景之间，转移瘤数量的差异尤为显著。场景A与场景B之间的转移瘤数量差值为3901个，场景C与场景D之间则为2093个。与之相比，肿瘤总质量达到1千克的时间节点仅分别向后延迟了12天或52天。