TGA raw data from Fabrication and characterization of electrospun poly(e-caprolactone) fibrous membrane with antibacterial functionality

This research study is mainly targeted on fabrication and characterization of antibacterial poly(e-caprolactone) (PCL) based fibrous membrane containing silver chloride particles. Micro/nano fibres were produced by electrospinning and characterized with TGA, DSC, SEM and mechanical analysis. It was found that addition of silver particles slightly reduced onset of thermal degradation and increased crystallization temperature of neat PCL. Silver-loaded samples exhibited higher tensile stress and lower strain revealing that the particles behaved as reinforcing agent. Moreover, addition of silver chloride resulted in beaded surface texture and formation of finer fibres as opposed to the neat. Antibacterial properties were tested against Gram-negative and Gram-positive bacteria and remarkable biocidal functionalities were obtained with about six logs reduction of <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> O157:H7.

本研究主要聚焦于含氯化银颗粒的抗菌聚己内酯（poly(e-caprolactone), PCL）基纤维膜的制备与表征。研究采用静电纺丝技术制备微/纳米纤维，并通过热重分析（Thermogravimetric Analysis, TGA）、差示扫描量热法（Differential Scanning Calorimetry, DSC）、扫描电子显微镜（Scanning Electron Microscopy, SEM）以及力学性能分析对其进行表征。结果发现，银颗粒的引入会略微降低纯PCL的热降解起始温度，同时提高其结晶温度。载银样品展现出更高的拉伸应力与更低的断裂应变，表明该颗粒可作为补强剂发挥作用。此外，与纯PCL纤维相比，氯化银的添加会使纤维表面形成串珠状形貌，并制备出更细的纤维。研究针对革兰氏阴性菌与革兰氏阳性菌开展了抗菌性能测试，结果显示样品具备显著的杀菌功能，对金黄色葡萄球菌（Staphylococcus aureus）与大肠埃希氏菌O157:H7（Escherichia coli O157:H7）的菌落数可降低约6个对数级。