OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer

Evaluation of feasibility of adding aflibercept to an oxaliplatin-based regimen rather than a continuous administration of chemotherapy until progression, in order to decrease the risk of severe toxicities.

评估在基于奥沙利铂（oxaliplatin）的治疗方案中联合阿柏西普（aflibercept），而非持续化疗直至疾病进展的临床可行性，以降低严重治疗相关毒性反应的发生风险。